Novel anti-platelet aggregation polypeptides fromVipera lebetinavenom: Isolation and characterization

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Novel anti-platelet aggregation polypeptides from Vipera lebetina venom: isolation and characterization.

Lebetins 1 and Lebetins 2, two polypeptide groups that inhibit platelet aggregation, were isolated from Vipera lebetina venom by gel filtration and reverse phase chromatography. Amino acid sequencing indicated that the first group contains two major polypeptides of 13 and 12 residues; their molecular weight was determined by electrospray mass spectrometry. The second was composed of two peptide...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1996

ISSN: 0014-5793

DOI: 10.1016/0014-5793(96)00774-0